Isolated Lung Metastasis Prostate Cancer

Abstract

Introduction and importance: Prostate cancer is the second most diagnosed malignancy (after lung cancer) in men worldwide. The most common site for metastasis of prostate cancer is bone (84%), followed by distant lymph nodes (10.6%), liver (10.2%), and lung being the least with 9.1%. Isolated lung metastasis is very rare and is present in less than 4.6% of metastatic prostate cancer. This is the first case of de novo isolated lung metastasis of prostate cancer in our setting. Case presentation: We report a case of an 81-year-old male of African ethnicity who was diagnosed with isolated lung metastasis prostate adenocarcinoma. The total prostate specific antigen at the time of diagnosis was 182 ng/ml and grade group 3. Clinical discussion: The prognosis of prostate cancer patients with pulmonary metastasis is reported to be limited. Prostate cancer patients with lung metastasis have median overall survival of approximately 19 months. Conclusion: Although isolated pulmonary metastasis is rare in prostate cancer, it should not be excluded especially in patients with perineural invasion; however, further investigations are required to exclude metastasis to other sites.