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article · Food Chemistry Advances

Investigation of the metal complexes and bioactive compound formed by coordination of bioactive phytochemical from ginger (Zingiber officinale) extracts to metal ions

202347 citationsOpen accessDelta State University

In plain language

This study examined the bioactive compounds and metal complexes formed by combining ginger leaf extracts with zinc and copper ions. Crude extracts were produced using ethanol, distilled water, and n-hexane. The ginger extract dissolved in ethanol and distilled water but not in n-hexane, whereas the tested salts did not dissolve in these extracts. Phytochemical screening detected several constituents, including alkaloids, flavonoids, phenols, tannins, steroids, terpenoids, saponins, proteins, carbohydrates, and multiple forms of glycosides. Fourier transform infrared spectroscopy revealed amino and alcohol functional groups within the ethanol extract. Furthermore, an increase in functional group absorption peaks in the metal complexes demonstrated the formation of metal salts across diverse donor sites, confirming the presence of bioactive compounds in ginger.

Key takeaways

  • Ginger leaf extract dissolved in distilled water and ethanol but was insoluble in n-hexane.
  • Screening confirmed the presence of diverse phytochemicals, including alkaloids, flavonoids, phenols, and various glycosides.
  • Ethanol extracts of ginger leaves displayed amino and alcohol functional groups under infrared analysis.
  • Increased infrared absorption peaks indicated the coordination of zinc and copper salts with various donor sites in the extract.

Why it matters

Understanding how botanical extracts interact with essential metals such as zinc and copper helps clarify the chemical mechanisms of medicinal plants. By mapping functional groups and chemical donor sites, this research provides fundamental scientific insight into how active phytochemicals from ginger leaves coordinate with metal ions at a molecular level.

Commercialisation angle

This work represents early-stage laboratory research examining basic chemical coordination between plant extracts and metal ions. The abstract provides no indication of an applied development pathway, intended commercial users, or target consumer products.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

The Medicinal value of many plants is attributed to their bioactive compounds. The research is aimed to investigate the metal complexes and bioactive compounds formed from ginger extract. n-hexane, ethanol, and distilled water were used to generate crude extract from ginger leaves. Solubility of the ligand with the corresponding metal (Zn and Cu) complexes were measured. The Infra-red analysis of each extract was measured using FT-IR spectrometer. According to the findings, ginger extract was soluble in ethanol and distilled water but not n-hexane. The salts were not soluble in the ethanol, n-hexane and distilled water extract of ginger. In this investigation, significant phytochemicals were reported. Ginger contains phytochemicals like alkaloids, glycosides, anthraquinone glycosides, cardiac glycosides saponins, tannin, phenol, flavonoid, steroids, terpenoids, protein and carbohydrate. The ethanol extract contains amino and alcohol functional groups. The results of the study show that an increase in the functional groups' absorption peak in the metal complexes of ginger extracts indicates the occurrence of metal salts with varied donor sites in the plant extract. Hence, it may be concluded that ginger possesses bioactive compounds.

Research topics

  • Ginger and Zingiberaceae research
  • Ethnobotanical and Medicinal Plants Studies
  • Pharmacological Effects of Medicinal Plants

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DOI: 10.1016/j.focha.2023.100337

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