book chapter
Understanding environmental risk factors provides vital opportunities to comprehend cancer formation, molecular classification, and adverse developmental outcomes. The exposome encompasses the comprehensive evaluation of all environmental influences experienced by an individual across their lifespan, covering biological, chemical, and physical factors. Evidence indicates that exposures affecting both mothers and fathers before, during, and after conception significantly impact human pregnancy and fetal development. Detrimental environmental exposures include metals, volatile and persistent organic compounds, food chemicals, occupational hazards, agricultural chemicals, and air and water pollution. These exposures link directly to negative developmental endpoints such as growth restriction, premature birth, mortality, and various structural and functional abnormalities. Evaluating these factors provides a foundational overview of how surrounding environments shape biological risks from gametogenesis through to later disease states.
Everyday environmental surroundings play a substantial role in human health and development. Identifying how exposure to diverse chemicals, pollutants, and hazards affects parents and unborn children is essential for understanding pregnancy complications and long-term health challenges, including birth defects and cancer development.
The abstract outlines broad conceptual and biological links rather than a specific technology, so it does not indicate a commercialisation pathway or application distance. The insights are situated at the foundational research level, offering contextual understanding for environmental health risks.
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Risk factors provides a chance to comprehend the cancer formation, and its molecular classification. The exposome represents a thorough evaluation of all environmental factors that affect a person throughout their life, including biological, research has demonstrated the connection between adverse developmental outcomes, including growth restriction, preterm birth, and morphological and functional abnormalities, and environmental chemical exposures for both the mother and the father prior to, during, and following conception. According to recent studies, human pregnancy and development can be significantly impacted by environmental exposures to chemical, biological, and physical variables that both the mother and the father experience. Exposures associated with poor developmental outcomes include metals, volatile and persistent organics, chemicals in food, occupational exposures, agricultural chemicals, and pollution of the air and water. Premature birth, mortality, growth restriction, and structural and functional abnormalities are developmental endpoints linked to these exposures.
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DOI: 10.4018/979-8-3373-5796-6.ch001
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