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article · Journal of Biomolecular Structure and Dynamics

In silico molecular modeling and simulations of black tea theaflavins revealed theaflavin-3’-gallate as putative liver X receptor-beta agonist

20238 citationsOpen accessThe Federal Polytechnic, Ado-Ekiti

Abstract

) for absorption, distribution, metabolism, excretion, and toxicological properties. Our result revealed theaflavin TF2B as a putative LXR-beta agonist, possibly responsible for the widely observed hypocholesterolaemic effect in black tea. This finding, while encouraging, needs to be experimentally verified in wet studies.Communicated by Ramaswamy H. Sarma.

Research topics

  • Cholesterol and Lipid Metabolism
  • Atherosclerosis and Cardiovascular Diseases
  • Tea Polyphenols and Effects

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DOI: 10.1080/07391102.2023.2175264

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