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article · International Journal of Infectious Diseases

Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo

202341 citationsOpen accessUniversité de Kinshasa (UNIKIN)

Abstract

R561H and P441L observed in eastern DRC are a concern, as they are associated with delayed artemisinin-based combination therapies-clearance and candidate marker of resistance, respectively. This is consistent with previous observations of shared drug resistance profiles in parasites of that region with bordering areas of Rwanda and Uganda. The likely circulation of parasites has important implications for the ongoing surveillance of partial artemisinin-resistant P. falciparum and for future efforts to mitigate its dispersal.

Research topics

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Hepatitis C virus research

Sustainable Development Goals

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DOI: 10.1016/j.ijid.2023.11.026

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