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article · Cancer Control

<i>KRAS</i>, <i>NRAS</i> and <i>BRAF</i> Mutational Profile of Colorectal Cancer in a Series of Moroccan Patients

20247 citationsOpen accessMohammed V University

Abstract

Detection of <i>KRAS</i> mutations, particularly the G12 C subtype, may be significant for patients with CRC and has possible therapeutic implications. However, rare <i>KRAS</i> concomitant mutations in CRC patients suggest that each individual may present distinct therapeutic responses. <i>KRAS</i> testing alongside the identification of other affected genes in the same patient will make the treatments even more personalized by contributing more accurately to the clinical decision process. Overall, early diagnosis using novel molecular techniques may improve the management of CRC by providing the most efficient therapies for Moroccan patients.

Research topics

  • Colorectal Cancer Treatments and Studies
  • Genetic factors in colorectal cancer
  • Cancer Genomics and Diagnostics

Sustainable Development Goals

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DOI: 10.1177/10732748241262179

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