<i>Atriplex halimus</i>: Phytochemical Insights, Traditional Applications, and Pharmacological Promises

Abstract

Medicinal and aromatic plants are used in traditional medicine due to their diverse bioactive chemicals, Atriplex halimus is a saltbush that has an extensive background in traditional medicine giving it a strong argument for further ethnopharmacological research. We aimed in this comprehensive review by using different databases as to illustrate the phytochemical composition, the traditional uses, and the pharmacological properties of A. halimus. We evaluated the phytochemical composition, the traditional uses, and the pharmacological properties of A. halimus using specific words in the different databases such as Scopus, PubMed, and ScienceDirect who served as the foundation to our research, 68 articles were retrieved from those databases out of an initial pool of 180 articles. Our review study revealed the different traditional uses as well as the different families of compounds in A. halimus extracts, including phenolic acids, flavonoids, and alkaloids. These compounds exhibited various pharmacological effects, notably antioxidant, antibacterial, antidiabetic, scolicidal, and cytotoxic properties. The analysis of the gathered publications allowed us to categorize the phytochemicals, traditional applications, and pharmacological actions of A. halimus extracts. This review underscores the importance of A. halimus and highlights the presence of additional bioactive substances that remain unexplored but hold potential for future research. This review can serve as a guide for future investigations in this area.