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article · Expert Opinion on Drug Safety

Hypersensitivity reactions to biologics in chronic rheumatic diseases: prevalence and associated factors

Abstract

BACKGROUND: The aim of our study was to determine the prevalence of hypersensitivity reactions in patients with chronic rheumatic diseases (CRD) treated with biologic therapies, and to evaluate the associated factors. RESEARCH DESIGN AND METHODS: A 6-year retrospective, single-center study was performed, including patients with CRD treated with biologic therapies. RESULTS: = 0.01). CONCLUSIONS: Considering the predictive factors of hypersensitivity reactions to biologics in clinical practice could help anticipate risks and improve patient safety.

Research topics

  • Biosimilars and Bioanalytical Methods
  • Rheumatoid Arthritis Research and Therapies
  • Monoclonal and Polyclonal Antibodies Research

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DOI: 10.1080/14740338.2025.2567588

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