Histomorphology of Testes in Honey Treated Adult Male Albino Rats

Abstract

Objective: Present study was conducted to examine the histomorphology of testes and serum testosterone levels of adult male albino rats fed with honey.Materials and Methods: The albino rats were divided into four groups of eight per cage.Controls received drinking water.Groups A, B and C were fed with 0.15, 0.3 and 0.6 mL kgG 1 b.wt. of honey respectively twice a day, orally for four and eight weeks.Blood samples were obtained from 4 rats per group for testosterone estimation.Testes were excised for histomorphology.Results: After eight weeks, testes from control and honey-treated rats showed normal histoarchitecture, whereas four-week honey-treated rats showed decreased prominence of seminiferous tubules with prominent sertoli cells and reduction of leydig cells.After four weeks, honey-treated rats showed significant elevation in serum testosterone level (p<0.05),but after eight-week, no significant change (p>0.05) was observed, compared to controls.Conclusion: Honey consumption could have a short-term positive effect on testosterone secretion and may lead to hyperactive testicular cells.