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article · Scholars Journal of Medical Case Reports

Guidewire-Induced Distal Perforation of a Protected First Diagonal Branch During Mid-Left Anterior Descending Bifurcation Stenting: A Case Report

2026Open accessMohammed V University

In plain language

Coronary artery perforation during elective percutaneous coronary intervention is a severe complication that can cause cardiac tamponade and poses difficult management challenges. A clinical case involved a 76-year-old male presenting with paroxysmal supraventricular tachycardia and accelerating chronic coronary syndrome caused by significant stenosis in the mid-left anterior descending artery at the first diagonal bifurcation. During provisional stenting using a jailed guidewire to protect the diagonal branch, the patient experienced haemodynamic instability and cardiac tamponade due to distal perforation of the diagonal branch caused by the wire. Clinicians resolved the life-threatening situation and restored haemodynamic stability through emergency pericardiocentesis, blood transfusion, and the deployment of a covered stent across the mid-left anterior descending artery, which deliberately sacrificed the ostium of the diagonal branch to achieve a satisfactory outcome.

Key takeaways

  • Coronary artery perforation during bifurcation stenting can trigger rapid cardiac tamponade and severe haemodynamic instability.
  • A jailed protection guidewire caused an accidental distal perforation of the first diagonal branch during the procedure.
  • Immediate pericardiocentesis and blood transfusion were required to stabilise the patient.
  • Haemodynamic stability was achieved by deploying a covered stent across the main artery, deliberately sacrificing the diagonal branch ostium.

Why it matters

Percutaneous coronary interventions carry rare but critical risks where protective procedural steps can inadvertently cause severe internal bleeding around the heart. Demonstrating how clinicians address sudden perforations using emergency fluid drainage and covered stents provides valuable insights for medical teams navigating unexpected life-threatening complications during complex cardiovascular interventions.

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Abstract

The coronary artery perforation during elective percutaneous coronary intervention is a nightmare for interventional cardiologists and one of the most common complications that lead to cardiac tamponade and is always hard to manage timely and properly [1]. We report the case of a 76-year-old male who developed a paroxysmal supraventricular tachycardia with an accelerating chronic coronary syndrome due to a significant mid-left anterior descending artery [LAD] stenosis involving the first diagonal bifurcation. During provisional stenting of the mid-LAD with protection of the diagonal branch via a jailed guidewire, hemodynamic instability and cardiac tamponade occurred secondary to distal perforation of the first diagonal branch by the protection wire. Pericardiocentesis, transfusion and a covered stent deployed across the mid-LAD, deliberately sacrificing the diagonal branch ostium restored a hemodynamic stability and a satisfying result was achieved.

Research topics

  • Coronary Interventions and Diagnostics
  • Coronary Artery Anomalies
  • Cardiac Structural Anomalies and Repair

Sustainable Development Goals

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DOI: 10.36347/sjmcr.2026.v14i08.027

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