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article · Journal of Nanomaterials

Green versus Chemical Precipitation Methods of Preparing Zinc Oxide Nanoparticles and Investigation of Antimicrobial Properties

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In plain language

This research compared two methods for creating zinc oxide nanoparticles (ZnO NPs): a green synthesis approach using fruit extracts (avocado, mango, papaya) and a chemical precipitation method. The study characterised the resulting nanoparticles using techniques like FT-IR, XRD, and SEM, noting that green synthesis produced smaller particles (11-21 nm) compared to chemical methods (30-40 nm). Both types of ZnO NPs demonstrated strong antimicrobial properties against Bacillus subtilis, Staphylococcus aureus, and Salmonella typhimurium. Notably, the green-synthesised nanoparticles showed superior antimicrobial activity, with inhibition zones ranging from 15-24 mm, outperforming the chemical method's 7-15 mm. The green synthesis method was also identified as eco-friendly and safer.

Key takeaways

  • Zinc oxide nanoparticles can be synthesised using both green (fruit extract-based) and chemical precipitation methods.
  • Green synthesis produced smaller zinc oxide nanoparticles (11-21 nm) compared to chemical precipitation (30-40 nm).
  • Both types of nanoparticles exhibited strong antimicrobial properties against common bacteria, including Bacillus subtilis, Staphylococcus aureus, and Salmonella typhimurium.
  • Green-synthesised nanoparticles showed superior antimicrobial activity and were identified as more eco-friendly and safer than those produced chemically.

Why it matters

Developing effective antimicrobial agents is crucial for public health, especially with growing concerns about antibiotic resistance. This research offers a greener, potentially safer way to produce zinc oxide nanoparticles with strong antimicrobial capabilities, which could lead to new, environmentally conscious solutions for fighting bacterial infections.

Commercialisation angle

This early-stage research indicates that green-synthesised zinc oxide nanoparticles could be applied in antimicrobial products. Potential users might include industries developing disinfectants, wound dressings, or coatings for medical devices, seeking eco-friendly and effective antibacterial solutions. The abstract suggests a promising alternative to chemical synthesis, but further development and testing are needed to move towards real-world commercialisation.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

Comparison of green and chemical precipitation method syntheses of zinc oxide nanoparticles (ZnO NPs) was performed, and antimicrobial properties were investigated. Avocado, mango, and papaya fruit extracts were carried out for the green synthesising methods, while the chemical precipitation method was chosen from chemical synthesis methods. Zinc nitrate was used as a salt precursor, whereas leaf extract was served as a reducing agent for green synthesising methods. In addition, sodium hydroxide, polyvinyl alcohol, and potassium hydroxide were used as reducing agents in the case of chemical precipitation synthesis methods. ZnO NPs were characterised by characterizing techniques such as Fourier transform infrared (FT-IR), X-ray diffraction (XRD), and scanning electron microscopy (SEM). The antimicrobial activities of prepared nanoparticles were evaluated on Bacillus subtilis (B. subtilis), Staphylococcus aureus (S. aureus), and Salmonella typhimurium (S. typhimurium). The particle sizes of the prepared samples which were evaluated by the Scherrer equation were in the range of 11-21 nm for green synthesis, while 30-40 nm for chemical precipitation synthesis methods. Small agglomerations were observed from SEM results of prepared ZnO NPs from both methods. Prepared ZnO NPs were showed strong antimicrobial properties. From the result, the inhibition zone was in the range of 15-24 mm for the green route and 7–15 mm for chemical precipitation methods, where the standard drugs have 25 mm of the zone of inhibition. A green synthesised method of preparing ZnO NPs gives promising antimicrobial properties compared to chemical synthesis and is also eco-friendly and safe compared to the chemical synthesis.

Research topics

  • Nanoparticles: synthesis and applications

Read the original research

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DOI: 10.1155/2021/9210817

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