preprint · bioRxiv (Cold Spring Harbor Laboratory)
ABSTRACT In this study, Ag-MgONCs (silver-magnesium oxide nanocomposites) were fabricated using Talinum triangulare leaf extract as a renewable, mild reducing, and stabilizing agent. The synthesis process involved molecular interactions between pre-prepared AgNPs (silver nanoparticles) and in situ -prepared MgO. Confirmation of the nanocomposites came from micrographic images obtained through SEM-EDX analysis. Dynamic light scattering (DLS) revealed a characteristic nanocomposite size of 295 nm. The infrared spectrum (FTIR) proved interactions between T. triangulare and Ag. Additionally, X-ray patterns of AgNPs and Ag-MgONCs confirmed hexagonal and cubic crystalline states, respectively, with average particle sizes of 17 nm. Furthermore, an in vitro analysis against five bacterial strains ( Escherichia coli , Acinetobacter baumannii , Pseudomonas aeruginosa , Klebsiella pneumoniae , and Proteus mirabilis ) revealed pronounced activity of the nanocomposites, particularly against Proteus mirabilis , indicating bactericidal potential.
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DOI: 10.1101/2024.11.08.622651
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