MARATTO

article · Annals of Thoracic Surgery Short Reports

Giant Ulcerative Solitary Plasmacytoma of the Sternum: Resection with Reconstruction in a Resource-Limited Setting

In plain language

Solitary plasmacytoma of the sternum is an uncommon plasma cell tumour that presents severe clinical challenges, particularly in healthcare environments with limited resources. A clinical case involving a 48-year-old male presenting with a recurrent, ulcerating mass on the anterior chest wall illustrates this condition. Diagnostic imaging revealed extensive destruction of the sternal bone, which histopathological examination subsequently confirmed as a solitary bone plasmacytoma. Treatment involved radical surgical excision followed by chest wall reconstruction, which was achieved using pectoralis major flaps combined with improvised wiring techniques. Although the patient experienced a postoperative wound infection, clinical recovery at six months was favourable, and adjuvant radiotherapy was arranged. The outcome demonstrates that radical surgical management and reconstruction for complex chest wall tumours can be successfully carried out even within resource-constrained medical settings.

Key takeaways

  • A 48-year-old male presented with a recurrent, ulcerated anterior chest wall mass caused by a destructive solitary bone plasmacytoma of the sternum.
  • Surgical treatment required radical excision and chest wall reconstruction using pectoralis major muscle flaps and improvised wiring.
  • Despite a postoperative wound infection, the patient showed favourable recovery at six months with planned adjuvant radiotherapy.
  • Complex sternal resections and reconstructions are feasible using adaptive techniques in resource-limited healthcare settings.

Why it matters

Managing advanced tumours often requires complex reconstructive techniques and expensive materials that may not be available in low-resource hospitals. Demonstrating that successful chest wall reconstruction can be achieved using patient tissue and improvised wiring provides clinicians in resource-constrained environments with practical, adaptable surgical strategies to treat severe conditions without specialised prosthetics.

Commercialisation angle

The abstract does not indicate a commercialisation pathway, as it describes a clinical case managed with surgical adaptation and improvised materials rather than a proprietary product or technology.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

Solitary plasmacytoma of the sternum is a rare plasma cell neoplasm, challenging to manage in resource-limited settings. We present a 48-year-old man with a recurrent, ulcerated anterior chest wall mass. Imaging showed a destructive sternal lesion, confirmed as solitary bone plasmacytoma via histopathology. Radical excision and chest wall reconstruction using pectoralis major flaps and improvised wiring were performed. Postoperative wound infection occurred. At 6 months, recovery was favorable, with adjuvant radiotherapy planned. This case highlights diagnostic and reconstructive challenges and demonstrates feasible management in a low-resource setting.

Research topics

  • Multiple Myeloma Research and Treatments
  • Peptidase Inhibition and Analysis
  • Heparin-Induced Thrombocytopenia and Thrombosis

Sustainable Development Goals

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

DOI: 10.1016/j.atssr.2025.06.017

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.