article · Clinical Case Reports
Neuroblastoma is a solid tumour of the sympathetic nervous system that typically affects children and occurs only rarely in adults. It originates in the medullary region of the adrenal gland or sympathetic ganglia. A clinical case details the successful treatment of an 18-year-old female presenting with six months of abdominal swelling and tenderness. Diagnostic imaging identified a large retroperitoneal mass that displaced surrounding anatomical structures. After multidisciplinary planning, surgeons completely resected the giant tumour. Histopathological analysis confirmed the mass was an adrenal neuroblastoma. Following surgical removal, the patient received adjuvant chemotherapy. Over a nine-month follow-up period, she experienced favourable outcomes and remained free of symptoms. The findings highlight the critical role of thorough diagnostic investigation and a combined treatment approach involving surgery and chemotherapy for managing this rare presentation.
Neuroblastoma is predominantly known as a childhood cancer, making adult diagnoses challenging and rare. Demonstrating that combined multidisciplinary preparation, complete surgical resection, and subsequent chemotherapy can yield disease-free survival helps clinicians understand how to approach and treat this rare oncological condition in adult patients.
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Neuroblastoma (NB) is a rare solid tumor of the sympathetic nervous system, primarily occurring in children and rarely in adults. Its extracranial origin stems from the medullary region of the adrenal gland or sympathetic ganglia. We report an 18-year-old female who presented with a 6-month history of abdominal swelling and tenderness. Imaging revealed a large retroperitoneal mass causing significant displacement of adjacent structures. Following multidisciplinary optimization, a huge tumor was successfully resected surgically. Histopathology confirmed the diagnosis of adrenal NB. The patient underwent adjuvant chemotherapy and remained symptom-free with favorable outcomes during a 9-month follow-up. This case underscores the importance of comprehensive diagnostic evaluation and multimodal management in treating rare adult adrenal NB.
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DOI: 10.1002/ccr3.70453
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