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article · Drug Design Development and Therapy

Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies

20248 citationsOpen accessZagazig University

Abstract

Ger reduced the oxidative stress status, neuroinflammation and apoptosis and activated GABAergic neurotransmission, which might clarify its anticonvulsant. Ger protects animals against PTZ prompted kindling as established by the enhancement in short term as well as long-term memory. Ger mitigated the injury induced by Glu in NGF prompted PC12 cell.

Research topics

  • Medicinal Plants and Neuroprotection
  • Anesthesia and Neurotoxicity Research
  • Neuroinflammation and Neurodegeneration Mechanisms

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DOI: 10.2147/dddt.s481985

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