article · Frontiers in Chemistry

Formulation and characterization of cholesterol-based nanoparticles of gabapentin protecting from retinal injury

Hatem I. Mokhtar
Ahmed R. Gardouh
Nehal M. Elsherbiny
Sharifa Alzahrani
Reem Alshaman
Mohamed K. El-Kherbetawy
Esam Sayed Ahmed
Dina M. Khodeer
Esam Ghanem Abu El Wafa
Mona Qushawy
Sawsan A. Zaitone

20244 citationsOpen accessSuez Canal University

Abstract

The preparation of GAB-SLNs enhanced the physical properties of gabapentin and improved its biological activity as a neuroprotectant. Further studies are warranted to validate this technique for the use of oral gabapentin in other neurological disorders.

Research topics

Lipid Membrane Structure and Behavior
Retinal Diseases and Treatments
Advanced Drug Delivery Systems

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.3389/fchem.2024.1449380

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