Fetal Middle Cerebral to Uterine Artery Pulsatility Indices Ratios in Preeclampsia versus Normal Pregnancy

Abstract

Objectives: To assess the predictive value of MCA/uterine artery pulsatility indices (PI) ratio in the third trimester of pregnancy for anticipating adverse pregnancy outcomes in women with preeclampsia, comparing it to the CPR (MCA/umbilical artery PI ratio).Study Design: A prospective study.Patients and Methods: The research involved 50 preeclampsia cases and 50 healthy pregnancies or births that were more than 26 weeks old. All participants underwent comprehensive laboratory testing, comprising Urine analysis, CBC, liver function tests, and renal function testing. Additionally, ultrasonography examinations were carried out at Benha University Hospital during the study period.Results: In the preeclampsia group, the mean MCA PI, MCA/UTA, and MCA/Umbilical artery PI were lower, while the mean uterine and umbilical artery PI were higher in contrast to control group, and these differences were statistically significant. Negative newborn results, such poor APGAR scores, preterm birth, NICU admission, SGA, and neonatal death, were all more prevalent in the preeclamptic group in contrast to control group, with significant differences variations observed. MCA/UTA ratio in pregnancies with preeclampsia demonstrated its effectiveness as a valuable predictor of adverse neonatal outcomes. Conclusion: The Cerebro-Uterine (CU) ratio was notably different between the two groups, being less in preeclampsia cases in contrast to control group. Furthermore, it was significantly linked to poor neonatal results. in pregnancies affected by preeclampsia. The CU ratio displayed a commendable ability to predict adverse neonatal outcomes