FEATURES OF ASYMPTOMATIC HYPERURICEMIA IN PATIENTS WITH DIABETES MELLITUS TYPE 2 AND CONCOMITANT ESSENTIAL ARTERIAL HYPERTENSION

Abstract

The article analyzes the frequency of asymptomatic hyperuricemia in association with disturbance of carbohydrate metabolism, lipid metabolism, inflammatory process and kidney changes in patients with diabetes mellitus type 2 (DM 2) and concomitant essential arterial hypertension (EAH).The objective of this study was to determine the frequency of asymptomatic hyperuricemia in patients with diabetes mellitus type 2 and concomitant essential arterial hypertension and their effects on the main indicators of comorbid pathology.Material and methods. 125 patients were examined: 25 patients with essential arterial hypertension, stage II (Group I), 25 patients with subcompensated diabetes mellitus type 2 (group II) and 75 patients with subcompensated diabetes mellitus type 2 and concomitant essential arterial hypertension (group III).Results. Asymptomatic hyperuricemia, with an increase in uric acid levels in the blood of more than 410 μmol / L was observed in 36.0% of patients in group І, in 24.0% of patients in group II and in 46.7% of patients in group ІІІ. Relevant correlations have been found between the level of uric acid in the blood and the level of systolic blood pressure, glycosylated hemoglobin, dyslipidemia, inflammatory process and kidney damage.Conclusion. Asymptomatic hyperuricemia has a negative effect on the main indicators of comorbid pathology - in this case, diabetes mellitus type 2 and concomitant essential arterial hypertension.