article · Infection and Drug Resistance

Facile Synthesis of 5-Bromo-N-Alkylthiophene-2-Sulfonamides and Its Activities Against Clinically Isolated New Delhi Metallo-β-Lactamase Producing Klebsiella pneumoniae ST147

Mnaza Noreen
Tawaf Ali Shah
Mohammed Bourhia
Nasır Rasool
Yousef A. Bin Jardan
Muhammad Bılal
Muhammad Usman Qamar
Abid Mahmood
Sobia Umar Din
Lahcen Ouahmane

20244 citationsOpen accessUniversité Ibn Zohr

Abstract

The 5-bromo-N-alkylthiophene-2-sulfonamides displayed antibacterial efficacy against New Delhi Metallo-β-lactamase producing Klebsiella pneumoniae ST147. After the in-vivo trial, this substance might offer an alternative therapeutic option.

Research topics

Antibiotic Resistance in Bacteria
Pharmaceutical and Antibiotic Environmental Impacts
Phenothiazines and Benzothiazines Synthesis and Activities

Sustainable Development Goals

Life on Land

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DOI: 10.2147/idr.s455979

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