article · PLoS ONE

Extended-Spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 among diarrheic patients in Shashemene, Ethiopia

Shimelis Teshome Ayalneh
Yeonji Jeon
Solomon Gebre-Selassie
Se Eun Park
Mekonnen Teferi
Biruk Yeshitela Beshah
Seifegebriel Teshome
Tomas Getahun
Woldaregay Erku Abegaz

20242 citationsOpen accessAddis Ababa University

Abstract

The E. coli O157:H7 isolates in this study showed a significant resistance to certain antimicrobials that were tested. The level of ESBL and Carbapenemase production among these isolates was found to be quite high. We observed a high resistance to Ampicillin and Amoxicillin/Clavulanic acid among the ESBL and carbapenemase producing isolates. Ciprofloxacin was found to be the most effective drug against both the ESBL producers and nonproducers.

Research topics

Antibiotic Resistance in Bacteria
Escherichia coli research studies
Salmonella and Campylobacter epidemiology

Sustainable Development Goals

Sustainable Cities and Communities

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DOI: 10.1371/journal.pone.0306691

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