Expression level of matrix metalloproteinases -1, -2 and -9 associated with pelvic organ prolapse: experimental analytical study of round ligaments of Congolese women in two hospitals from the city of Kananga in Democratic Republic of Congo

Abstract

the expression level of matrix metalloproteinases is increased in patients with pelvic organ prolapse and is associated with this condition, matrix metalloproteinases-1 and -9 are associated with the occurrence of pelvic organ prolapse. These results will serve as a basis for experimental research studies of inhibitory evidence of estrogens and progesterone on these matrix metalloproteinases in our city with a view to adding these hormones as a means of preventing pelvic organs prolapse in women at risk in our city of Kananga.