review · Annals of Medicine and Surgery
Neuroplasticity offers substantial promise for aiding recovery after a stroke, yet applying it effectively in rehabilitation faces several practical hurdles. Key difficulties include how individual patients respond differently to treatments, determining the most effective timing and duration for therapies, and accounting for diverse clinical and sociocultural factors. Evidence highlights that rehabilitation must be tailored directly to specific patient characteristics to maximise recovery outcomes. While these limitations complicate standard implementation, the transformative role of neuroplastic mechanisms remains significant. Advancing clinical practice and ongoing research requires interdisciplinary collaboration alongside a deeper understanding of patient variation. Aligning therapy schedules with individual profiles and context will be essential for fully realising the restorative power of neuroplasticity in stroke care.
Stroke recovery can be an inconsistent process affecting individuals and healthcare systems globally. Understanding how the brain adapts through neuroplasticity provides a pathway to better therapeutic approaches. Identifying the limitations of standardised treatments and moving towards personalised rehabilitation can help clinicians deliver more effective care tailored to the specific timing and clinical needs of individual patients.
The findings point towards applications in personalised rehabilitation regimens and clinical decision frameworks for healthcare providers and therapy specialists. However, as a narrative review synthesising existing literature, the work is at an early conceptual stage. Developing these insights into commercial clinical tools or standardised therapeutic protocols will require further applied research, validated intervention designs, and interdisciplinary development.
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This review aims to assess the role of neuroplasticity in facilitating stroke recovery and identify the challenges and limitations associated with its implementation. A comprehensive literature search was conducted to identify relevant studies, which were meticulously evaluated to determine the potential solutions for effectively harnessing neuroplasticity. The results indicate that neuroplasticity holds significant promise in stroke rehabilitation; however, individual variability in response to interventions, timing and duration of interventions and sociocultural and clinical factors pose challenges. Tailoring interventions to individual patient characteristics is crucial for optimising the impact of neuroplasticity. Despite challenges and limitations, the transformative potential of neuroplasticity in stroke rehabilitation is undeniable. The abstract concludes by emphasising the importance of a comprehensive understanding of individual variability, optimising intervention timing and duration and considering sociocultural and clinical factors. Future research and clinical practice should prioritise personalised interventions and interdisciplinary collaborations to fully exploit the vast potential of neuroplasticity in stroke recovery.
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DOI: 10.1097/ms9.0000000000001137
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