article · Frontiers in Pharmacology

Exploring the CD3/CD56/TNF-α/Caspase3 pathway in pyrethroid-induced immune dysregulation: curcumin-loaded chitosan nanoparticle intervention

Nawal Alsubaie
Yasmina M. Abd‐Elhakim
Nawal Helmi
Amany Abdel-Rahman Mohamed
Afnan M. Alnajeebi
Badriyah S. Alotaibi
Tarek Khamis
Mohamed M.M. Metwally
Mai A. Samak
Wedad Mawkili
Amirah Albaqami
Sanaa Eissa

20251 citationOpen accessKafr el-Sheikh University

Abstract

The findings of this study highlighted the immunosuppressive effects of FTN and suggested the involvement of many CD cell markers as a potential underlying mechanism. Additionally, the results demonstrated the effectiveness of CML-CNP in mitigating pollutant-induced immune disorders.

Research topics

Curcumin's Biomedical Applications
Retinoids in leukemia and cellular processes
Pharmacological Effects of Natural Compounds

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DOI: 10.3389/fphar.2025.1505432

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