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article · American Journal of Tropical Medicine and Hygiene

Exclusive Breastfeeding and Clinical Malaria Risk in 6-Month-Old Infants: A Cross-Sectional Study from Kinshasa, Democratic Republic of the Congo

201624 citationsOpen accessUniversité de Kinshasa (UNIKIN)

In plain language

The World Health Organization recommends exclusive breastfeeding for an infant's first six months of life, yet its relationship with malaria risk has remained uncertain. A cross-sectional investigation examined infants at six months of age in the Democratic Republic of the Congo, comparing 137 exclusively breastfed infants against 358 infants who were not exclusively breastfed. Each child underwent assessment for fever and was tested for malaria infections using polymerase chain reaction methods. The findings revealed that exclusive breastfeeding was linked to a significantly decreased risk of developing clinical malaria, yielding an odds ratio of 0.13. These results point to a clear protective effect offered by exclusive breastfeeding against symptomatic malaria infections in early infancy. Such evidence reinforces current infant feeding recommendations by demonstrating a vital health benefit in a malaria-endemic setting.

Key takeaways

  • A study evaluated 137 exclusively breastfed infants and 358 non-exclusively breastfed infants at six months of age in the Democratic Republic of the Congo.
  • Infants were tested for fever and malaria infections using polymerase chain reaction diagnostics.
  • Exclusive breastfeeding was associated with a substantially lower risk of clinical malaria, with an odds ratio of 0.13.
  • The findings suggest a protective effect of exclusive breastfeeding against clinical malaria during the first six months of life.

Why it matters

Malaria represents a severe threat to infant health in endemic regions, making non-pharmaceutical protective factors critically important. By demonstrating that exclusive breastfeeding significantly reduces the risk of clinical malaria in six-month-old infants, these findings provide essential empirical support for international infant feeding guidelines. Healthcare initiatives can leverage this evidence to encourage sustained exclusive breastfeeding, helping protect vulnerable infants against clinical infection in early life.

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Abstract

The World Health Organization recommends exclusive breastfeeding (EBF) for the first 6 months of life. However, the effect of EBF on malaria risk remains unclear. In the present study, 137 EBF infants and 358 non-EBF infants from the Democratic Republic of the Congo were assessed for fever and malaria infections by polymerase chain reaction, at 6 months of age. EBF was associated with a reduced risk of clinical malaria (odds ratio = 0.13; 95% confidence interval = 0.00-0.80), suggesting a protective effect of EBF against malaria.

Research topics

  • Child Nutrition and Water Access
  • Infant Nutrition and Health
  • Parasites and Host Interactions

Sustainable Development Goals

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DOI: 10.4269/ajtmh.16-0011

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