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article · The Cleft Palate-Craniofacial Journal

Evaluation of Secondary Alveolar Cleft Reconstruction With Labial and Palatal Lateral Ramus Cortical Grafts: A Case-Series Study

Abstract

Objective The study aims to evaluate a lateral ramus cortical graft technique for secondary alveolar bone grafting (SABG) in alveolar clefts. Design This study is a prospective case series. Settings From October 2024 to October 2025. Patients/Participants Seven patients of both sexes with unilateral alveolar clefts with an age range of 11 to 15 years old. Main Outcome Measure(s) The radiographic 3-dimensional volumetric calculation of graft fill, bone-bridge formation, and graft resorption rates. Intervention The cleft defects were reconstructed by the harvest of the mandibular lateral ramus cortical plate, which was cut and adapted to frame the labial and palatal cleft boundaries, while obliterating the intercancellous space with a mixture of cancellous particulates and allogenic demineralized bone matrix (DBM), covered by a collagen membrane. Results All grafts were consolidated with acceptable volume. The calculation of the generated models counted: 3.94 ± 0.30 cm 3 for volume cleft, 4.41 ± 0.38 cm 3 for volume graft, and 3.77 ± 0.36 cm 3 for volume bone bridge, with a graft fill rate of 1.12, bone bridge formation rate of 95.6%, and graft resorption rate of 14.51%. Conclusion The lateral ramus plate enabled a nearby intramembranous graft to achieve structural integrity and minimal morbidity, with favorable graft fill, bone bridge formation, and resorption rates. Mixing cancellous particulates with allogenic DBM and collagen membrane coverage compensated for the limited cancellous abundance at the donor site and enhanced the graft's osteogenic potential.

Research topics

  • Cleft Lip and Palate Research
  • Dental Implant Techniques and Outcomes
  • Craniofacial Disorders and Treatments

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DOI: 10.1177/10556656261431472

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