Evaluation of pulpal response to Endosequence root repair versus Biodentine after pulpotomy in primary teeth of puppies

Abstract

Background: Bioceramics are widely used as vital pulp therapy biomaterials given their excellent biocompatible and antibacterial properties. Aim: the aim of the study was to evaluate the characteristics of the remaining pulp tissue after Endosequence root repair versus Biodentine pulpotomy in puppies’ primary molars and canines. Material and Methods: Twenty-four primary molars and canines in 4 mongrel puppies underwent total pulpotomy procedure using Endosequence root repair and Biodentine. After 4 weeks, areas beneath the pulpotomy sites were subjected to histologic examination and pulpal response evaluation in terms of: inflammatory cell response, tissue disorganization, and hard tissue formation. Mann Whitney test was used for ordinal response variables, to compare between the two groups.Results: No statistically significant difference was detected between both groups regarding all pulpal response parameters Conclusions: Both Biodentine and Endosequence root repair presented biocompatibility allowing for preserved pulp vitality and the formation of hard tissue barrier in primary teeth of puppies.