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article · Anais Brasileiros de Dermatologia

Evaluation of immunohistochemical and gene expression of Janus kinase 1 and Janus kinase 3 in the skin of different clinical types of mycosis fungoides patients – Part 1

2026Open accessTanta University

Abstract

JAK1 and JAK3 were significantly expressed in MF skin lesions in comparison to normal controls. JAK1 and JAK3 were more expressed in the tumor stage than patch and plaque stage MF, suggesting that JAK1 and JAK3 could play a crucial role in MF pathogenesis, progression, and prognosis.

Research topics

  • Cutaneous lymphoproliferative disorders research
  • Lymphoma Diagnosis and Treatment
  • CNS Lymphoma Diagnosis and Treatment

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DOI: 10.1016/j.abd.2026.501299

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