Evaluation of Antibody Titre in Dogs Vaccinated against Canine Parvovirus in Jos, Plateau State, Nigeria

Abstract

Canine parvoviral enteritis is a highly contagious disease with fatal outcomes, in most cases populations with high morbidity and mortality rate. The study was conducted to determine the immune status of dogs vaccinated against Canine Parvovirus (CPV) using enzyme linked immunosorbent assay (ELISA). Sixty randomly selected dogs were used for the study, out of which four had no level of determined antibody titre (1-2 S – unit), fifty six had protective immunity (3-6 S-unit) which comprised 24 (40%) males and 36(60%) females. Among the males, 23(95.83%) were protective while 33(91.67%) among the females were protective. A total of 17 dogs were puppies and all had protective immunity (3-6 S-unit) while 43 were adults out of which 39 (90.70%) had protective immunity (3-6 S-unit). A total of 30 dogs were sampled from each local government area out of which 28(93.33%) had protective immunity (3-6 S unit) in each local government. The breeds included in the study were Caucasian, Mongrel, Rottweiler, Lhasa, Bull mastiff and German Shepard out of which all had protective immunity 56(93.33%) (3-6 S-unit) except 4(6.67%) for Caucasian that were unprotected. Based on the number of primary vaccinations, 3 dogs had single, 4 dogs had double and 52 dogs had triple primary vaccination out of which 56 dogs had protective antibody titre (3-6 S-unit). There was no significant difference (P>0.05) between sex, age, location, breeds and level of immunity while there was a significant difference (P< 0.05) between the number of primary vaccination and immune titre of the dogs sampled