article · Current Pharmaceutical Biotechnology

Essential Oils from Olea europaea and Cyperus esculentus ExhibitPromising Therapeutic Effect against Alzheimer's Disease in a Rat Model

Gamal M. Hamad
Adel I. Abd Elaziz
Sanaa S. A. Kabeil
Mohamed H. El-Sheikh
Nour Abdo
Hazem S. Elshafie
Sawsan Abd Ellatif
Naser A. Alkenani
Elsayed S. Abdel Razik
Sarah Abd-Elmohsen Abou-Alella
Marwa A. Saad
Ippolito Camele

20251 citationAlexandria University

Abstract

The study suggests that serum biomarker gene expression profiles could serve as valuable indicators for differentiating between Alzheimer's disease, virgin olive oil, and dietary treatments. Both virgin olive oil and tiger nut essential oil demonstrated protective effects, enhancing cognitive function and offering therapeutic potential against AD symptoms. These effects were achieved through the reduction of inflammation, the inhibition of AChE activity, and the reduction of amyloid-beta accumulation.

Research topics

Pharmacological Effects of Medicinal Plants

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DOI: 10.2174/0113892010343085250226111914

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