MARATTO

article · Frontiers in Pharmacology

Empagliflozin attenuates dexamethasone-induced non-alcoholic steatohepatitis by regulation of ferroptosis, inflammation and autophagy

2026Open accessMansoura University

Abstract

EMPA effectively ameliorated DEXA-induced NASH via reducing liver damage caused by excess iron by restoring the appropriate levels of iron, preventing ferroptosis, restoring lipid homeostasis, reducing oxidative stress, and managing inflammation and fibrosis.

Research topics

  • Ferroptosis and cancer prognosis
  • Cancer, Lipids, and Metabolism
  • Cholesterol and Lipid Metabolism

Sustainable Development Goals

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

DOI: 10.3389/fphar.2026.1741926

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.