Electrochemical contribution to the treatment of cancerous cells by a therapeutic plant

Abstract

In this project, we have successfully developed an electrochemical biosensor based on carbon graphite for the detection and alteration of the morphology of cancer cells. We studied the effect of electrochemical methods associated with the presence of a medicinal plant extract. The results we obtained are very promising, as complete destruction of cancer cells was observed after 48 h. The use of electrochemical biosensors for the diagnosis and treatment of cancer has shown great potential in recent years. In this study, we used a graphite carbon electrode to detect and monitor changes in cancer cell morphology. We also evaluated the effectiveness of a medicinal plant extract to improve the electrochemical response of the biosensor. Our results indicate that the electrochemical biosensor was very sensitive and specific in detecting cancer cells, and the addition of the herbal extract significantly improved its performance. After 48 h of exposure to the biosensor and plant extract combination, the cancer cells were completely destroyed, indicating the potential of this approach in the treatment of cancer. Overall, our study highlights the efficacy of electrochemical biosensors in the detection and treatment of cancer, and the promising role of medicinal plants in enhancing their performance. Further research is needed to explore the full potential of this approach and translate it into clinical applications. • A new biosensor based on carbon graphite in RPMI 1640 medium was designed and electrochemically characterized. • The biosensor (CPE-RPMI 1640) showed a clear electrochemical response to cancer cells. • The introduction of an Acacia heterophyllum extract into the electrolytic medium resulted in the degradation of cancer cells after 48 h at 37°C, compared with their previous electrochemical activation.