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article · Journal of International Medical Research

Efficacy of a multimodal conservative rehabilitation program for bladder control in individuals with incomplete spinal cord injury: A randomized controlled trial

2026Open accessMenoufia University

In plain language

A randomised controlled trial assessed the effectiveness of an eight-week multimodal conservative rehabilitation programme for managing bladder dysfunction in individuals with incomplete spinal cord injury. The study involved 74 male participants experiencing overactive bladder resulting from their injuries, divided into an experimental group and a control group. Participants completed three sessions per week over an eight-week intervention period, with assessments conducted at baseline, immediately after completion, and at an eight-week follow-up. Key evaluations targeted urodynamic metrics, pelvic floor muscle strength, and the severity of urinary incontinence. The findings revealed that the experimental group achieved statistically significant improvements across all measured outcomes compared to the control group. Overall, the multimodal regimen proved effective at improving bladder capacity, increasing pelvic floor muscle strength, and reducing incontinence in this patient group.

Key takeaways

  • An eight-week multimodal rehabilitation programme delivered three times weekly significantly improved bladder function in men with incomplete spinal cord injury.
  • Participants receiving the multimodal intervention demonstrated superior gains in pelvic floor muscle strength compared to the control group.
  • The intervention effectively reduced urinary incontinence severity and enhanced bladder capacity, with benefits sustained through an eight-week follow-up.

Why it matters

Overactive bladder is a debilitating consequence of incomplete spinal cord injuries that severely diminishes daily quality of life. Demonstrating that a structured, non-invasive rehabilitation programme can strengthen pelvic floor muscles and improve continence offers clinicians a viable conservative care pathway to restore vital urinary function without necessarily relying immediately on surgical or pharmacological options.

Commercialisation angle

This research provides applied and clinically tested evidence for a conservative, multimodal therapy protocol. It could be adopted by neuro-rehabilitation clinics, physiotherapists, and specialised spinal injury centres treating male patients with neurogenic bladder dysfunction. Because the intervention has completed a clinical trial showing positive follow-up outcomes, it is well positioned for clinical implementation, though formal standardisation and broader operational guidelines would facilitate wider health service integration.

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Abstract

Objective The study aimed to evaluate the efficacy of a multimodal intervention on urodynamic outcomes, urinary incontinence severity, and pelvic floor muscle strength in individuals with overactive bladder after incomplete spinal cord injury. Methods A single-blind randomized controlled trial was conducted on 74 male participants diagnosed with overactive bladder and incomplete spinal cord injury. Participants were randomly assigned to an experimental group or a control group. Treatment was conducted for 8 weeks, three sessions per week. Outcomes were assessed at baseline, post-intervention, and the 8-week follow-up. Results The experimental group showed significantly greater improvements in the measured outcomes compared with the control group (P < 0.001). Conclusion Incorporating a multimodal regimen demonstrated significant efficacy in enhancing bladder capacity, continence, and muscle function in individuals with overactive bladder due to incomplete spinal cord injury. Clinical trial registry (ID: NCT07008157). https://clinicaltrials.gov/study/NCT07008157?cond=Spinal%20Cord%20Injuries&intr=Multimodal%20Rehabilitation%20Program&viewType=Card&rank=1

Research topics

  • Urinary Bladder and Prostate Research
  • Pelvic floor disorders treatments
  • Spinal Cord Injury Research

Sustainable Development Goals

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DOI: 10.1177/03000605261464292

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