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article · PLoS ONE

Efficacy and safety of prazequantel for the treatment of Schistosoma mansoni infection across different transmission settings in Amhara Regional State, northwest Ethiopia

20244 citationsOpen accessBahir Dar University

Abstract

A single dose of 40 mg/kg PZQ was efficacious and safe for the treatment of S. mansoni infection when it was evaluated by the KK test, but a lower efficacy was recorded when it was evaluated by the POC-CCA test. However, the POC-CCA test's specificity, clearance time of CCA from urine after treatment, and interpretation of weakly reactive (trace) test results need further research.

Research topics

  • Parasites and Host Interactions
  • Global Maternal and Child Health
  • Child Nutrition and Water Access

Sustainable Development Goals

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DOI: 10.1371/journal.pone.0298332

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