Effects of Moderate Intensity Aerobic Exercise on Blood Coagulation and Fibrinolysis in Post-Menopausal Hypertensive Women.

Abstract

Objectives: This study was conducted to determine how postmenopausal hypertensive women’s blood coagulation and fibrinolysis parameters are affected by moderate-intensity aerobic exercise. Material and Methods: Fifty hypertensive female cases aged 50 to 65 took part in the trial, with BMIs ranging from 25 to 34.9 kg/m2. (Overweight and class 1 obesity). The cases were randomly allocated into the control and research groups. The control group (group A), which was under medical supervision, obtained anticoagulation medication. While the research group (group B) , which was under medical supervision, got anti-coagulation medication and moderately intense aerobic exercise in the form of three sessions each week for eight straight weeks of walking on an electronic treadmill for 40 to 50 minutes each sessions. Initial and two-month follow-up visits involve laboratory testing to measure clotting time, plasminogen activator inhibitor-1 (PAI-1), and to record systolic and diastolic blood pressure before and after the research. Results: Both groups’ clotting times markedly increased in favor of the study group by 7.01%, and the study group noticeably decreased PAI-1 (P< 0.05) compared to the control group by 19.18%. In contrast to the control group, the study group’s systolic and diastolic blood pressure were markedly lower (p< .05). Conclusion: In postmenopausal hypertensive women, moderate aerobic exercise markedly decreased arterial blood pressure and improved fibrinolysis by decreasing plasminogen activator inhibitor-1 (PAI-1) and lengthening the clotting time.