Effectiveness of Vinorelbine in the Management of Pseudomyogenic Hemangioendothelioma: A Case Report

Abstract

Pseudomyogenic hemangioendothelioma is an uncommon vascular neoplasm that has recently been identified as a distinct entity. Despite being classified as a malignant tumour and its often-worrisome clinical presentation, the progression typically involves relapses after surgery and a rather infrequent potential for metastasis. The authors present the clinical case of a pseudomyogenic hemangioendothelioma of the lower limb, its evolution to lymph node involvement and distant metastasis, and the effectiveness of vinorelbine in its management. Through this case report, the authors underscore the significance of a precise histological and immunohistochemical assessment considering the usual misdiagnosis as sarcoma or metaplastic carcinoma. They also emphasise the significance of observing the evolutionary aspects of this indolent tumour while outlining the therapeutic strategy and systemic therapies’ sequences to enhance the quality of life for these long survivors.