Effect of Sodium Butyrate and Origanium Vulgare on Growth Performance, Biochemical Profile, Immune Status and Carcass Traits of Broiler Chickens

Abstract

The principal goal of this research was to examine how the addition of sodium butyrate(SB) and Origanium vulgare (OV) to basal diet affects various aspects of broiler chickenproduction, including growth rate, biochemical markers, immune system function, andcarcass traits. Five hundred one-day-old chicks of Cobb breed (males and females) weredistributed at random way into five dietary treatment groups on floor pens, each grouphave 4 replicates (25 birds/replicate) and reared at a private farm. Group (G1) receivedbasal diet without any addition (negative control). Birds of groups 2, 3, 4 and 5 receivedbasal diet enriched with 500 g/ton sodium butyrate (SB), 500 g/ton Origanium vulgare(OV), 250 g/ton SB+OV and 500 g/ton SB+OV, respectively. At day 35 of rearing, the growthperformance, biochemical profile, immunity parameters and carcass traits were evaluated.Our study demonstrated that supplementing basal diet with SB and OV, alone and incombination, resulted in improvements in body weight gain and feed conversion ratio anddecreased levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST),total cholesterol (TC), triglycerides (TG) and malondialdehyde (MDA) but increased totalprotein (TP), albumin, globulin, albumin/globulin ratio, superoxide dismutase (SOD) andcatalase (CAT). It also increased levels of IgG and IgM and enhanced immunity as itelevated phagocytic activity, phagocytic index, lysozyme activity, and hemagglutinationinhibition (HI) antibody titer against NDV. It improved carcass traits of broilers as itincreased live weight and carcass weight and dressing percent (72.5%). It could beconcluded that supplementation of basal diet with SB and OV, alone and in combination,improved growth performance, biochemical parameters, immune status, and carcass traitsof broilers. Therefore, the utilization of sodium butyrate and Origanium vulgare as feedadditives can be used as an effective and beneficial approach in broiler chicken production.Both have hepatoprotective, antioxidant, and immunostimulant effects. The mechanisms ofaction underlying these effects require further study in broiler chickens.