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article · PLoS ONE

Effect of pharmacokinetically-relevant ivermectin concentrations on survivorship and fecundity of Anopheles coluzzii and Aedes aegypti in Burkina Faso: A laboratory experimental study

Abstract

IVM concentrations typically achieved in human plasma during MDA campaigns were sufficient to significantly reduce both survival and fecundity of wild type An. coluzzii, but had no measurable effect on Ae. aegypti. These findings highlight the species-specific response to IVM and support its potential role in integrated vector control strategies targeting malaria vectors in Africa.

Research topics

  • Parasitic Diseases Research and Treatment
  • Malaria Research and Control
  • Parasites and Host Interactions

Sustainable Development Goals

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DOI: 10.1371/journal.pone.0332677

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