Effect of Laparoscopic Ovarian Drilling in Obese Versus Lean Polycystic Ovary Syndrome Patients

Abstract

Objectives: To examine the menstrual cycle regularity, ovulation, hormonal profile before and after LOD, and pregnancy rate in both groups over a 3-months post-surgery period.Study Design: Prospective cohort research.Patients and Methods: The subjects of this prospective cohort research were ninety PCOS-positive infertile women ranging in age from 25 to 35. Each patient was randomly assigned to one of two groups: Patients who were overweight were also diagnosed with PCOS, whereas those who were slim were included in Group 1.Results: Obese PCO (Group 2) had considerably greater pregnancy measures at 1 and 3 months compared to Lean PCO (Group 1) (P<0.05), and they were significantly higher after 3 months compared to 1 month in both groups (P<0.05). Insignificant differences were observed in right and left ovarian flow index (FI) and vascularization flow index (VFI). Both groups showed substantial decreases in right and left ovarian FI and VFI after 1 and 3 months compared to baseline (P<0.05).Conclusions: PCOS is treated well by ovarian drilling. Although the mechanism of the relationship between body mass index and gonadotropins is unclear, obesity may affect luteinizing hormone and anti-mullerian hormone (AMH) levels after LOD, and LOD may improve fertility outcomes in obese PCOS patients.