article · New Journal of Chemistry

Dual targeted Ugi-bisamides induce caspase-mediated apoptosis and inhibit PI3K/mTOR signaling in NSCLC

20252 citationsPharos University in Alexandria

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Abstract

Ugi adduct 8 exhibited potent anti-cancer against NSCLC cancer cells though caspase-mediated apoptosis and PI3K/mTOR inhibition signaling pathway.

Research topics

Natural product bioactivities and synthesis
Carbohydrate Chemistry and Synthesis
Synthesis of Organic Compounds

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DOI: 10.1039/d5nj00670h

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