article · BMC Infectious Diseases

Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected

Kelvin M. Kimenyi
Mercy Y. Akinyi
Elisha Omer
Philip Bejon
Abdirahman I. Abdi
Bonface M. Gichuki
Shaban Mwangi
George Obiero
James M. Njunge
Tegan Gilmore
Juliana Wambua
Kioko Mwikali
Jean Langhorne
Lynette Isabella Ochola‐Oyier

20243 citationsOpen accessUniversity of Nairobi

Abstract

The priming effect of prior asymptomatic infection may explain the blunted acquisition of antibody responses seen to malaria antigens following natural exposure or vaccination in malaria endemic areas.

Research topics

Malaria Research and Control
Complement system in diseases
Invertebrate Immune Response Mechanisms

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1186/s12879-024-08973-2

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