Diagnostic Accuracy of Tomographic Ultrasound Imaging (TUI) in Depth of Myometrial Invasion and Cervical Stromal Invasion in Endometrial Carcinoma

Abstract

Abstract Background Endometrial cancer (EC) is the most common gynecological neoplasm Of female genital organ in developed countries accounting for 50% of all gynecological cancer. The imaging routine in preoperative assessment of EC differs amongst the gynecologists. The advantages of cross-sectional imaging are taken for granted in computed tomography and magnetic resonance imaging. Recently, tomographic ultrasound has introduced these advantages to sonographic volume imaging. Aim of the Work To evaluate the potential accuracy of 3D tomographic ultrasound imaging (TUI) coupled with power Doppler in comparison to computed tomography scan in the detection of depth of myometrial invasion and stromal invasion in endometrial cancer in relation to histopathology. Patients and Methods This cross-sectional study (Diagnostic purpose) included fifty biopsied women who are pathologically proven endometrial cancer for two years (December 2018- December 2020). This study conducted at Ain Shams university Maternity Hospital (Gynecology oncology unit) Results This study showed that 2D US (Invasion ≥50.0%), Doppler (Feeding vessel), TUI (Coherent vessels), TUI (Margin disruption) and CT (Invasion ≥50.0%) were significantly more frequent in cases with positive cervical stroma invasion. There was no statistical significant difference according to endometrium invasion (histopathology) regarding demographic characteristics and clinical presentation. Conclusion Endometrial cancer (EC) is the most common gynecological neoplasm of female genital organ in developed countries accounting for 50% of all gynecological cancer. 3D tomographic ultrasound imaging (TUI) coupled with power Doppler showing significant accuracy in the detection of depth of myometrial invasion and stromal invasion in endometrial cancer in relation to histopathology.