article · Clinical Infectious Diseases

Diagnostic Accuracy of LiquidArray MTB-XDR VER 1.0 for the Detection of <i>Mycobacterium tuberculosis</i> Complex, Fluoroquinolone, Amikacin, Ethambutol, and Linezolid Susceptibility

Erick Auma
Robin M. Warren
Yonas Ghebrekristos
Samantha Pillay
Moses Mburu
Brigitta Derendinger
Morten Rühwald
Elizabeth M. Streicher
Grant Theron
Rouxjeane Venter
Rencia Alberts
Adam Penn‐Nicholson
Margaretha de Vos

20241 citationOpen accessStellenbosch University

Abstract

LA-XDR met the minimum World Health Organization target product profile for a next-generation, sputum-based, moderate-complexity DST with high fluoroquinolone and ethambutol resistance sensitivity, moderate amikacin resistance sensitivity, and promise for linezolid resistance, for which more data are needed. Improved LA-XDR MTBC detection would reduce missed resistance.

Research topics

Antibiotics Pharmacokinetics and Efficacy
Microfluidic and Capillary Electrophoresis Applications
Innovative Microfluidic and Catalytic Techniques Innovation

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1093/cid/ciae614

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