article · Bioorganic Chemistry

Design and discovery of 1,4-dihydropyrimidinone-based noncovalent DprE1 inhibitors with integrated biological and computational validation against Mycobacterium tuberculosis

Fady H. Fayek
M Bayomi Said
Mai H. A. Mousa
Hanan H. Georgey
Nagwa M. Abdel Gawad

2026Egyptian Russian University

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Research topics

Tuberculosis Research and Epidemiology
Cancer therapeutics and mechanisms
Phosphodiesterase function and regulation

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1016/j.bioorg.2026.110256

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