article · Analytical Methods
M. This method is further extended to the quantification of BRM in a pharmaceutical ophthalmic solution and rabbit aqueous humor. To ensure the accuracy and precision of the developed method, the results of pharmaceutical formulation analysis are compared to a reported HPLC method, which showed no significant difference. Thus, this research demonstrates the potential of the developed electrochemical sensor for the accurate and reliable quantification of BRM in biological samples, providing valuable insights into its pharmacokinetics and pharmacodynamics. Eco-Scale (AES) and the Green Analytical Procedure Index (GAPI) tool are used to assess the greenness of this method, and this method proved to be environmentally friendly.
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DOI: 10.1039/d5ay01107h
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