article · Afro-Egyptian Journal of Infectious and Endemic Diseases
The coronavirus epidemic caused significant loss of life and disrupted daily existence and economic activity across the globe through lockdowns and movement restrictions. Standard management protocols and clinical trials struggled initially to curb the transmission rate and reduce high morbidity and mortality figures. In response, this work reviews the fundamental virology and pathogenesis of the infection alongside potential therapeutic interventions. By presenting this scientific information in a clear and accessible format, the review aims to provide researchers, healthcare practitioners, and the general public with knowledge that supports the overall control and potential eradication of the virus, while helping to prevent future resurgences.
Understanding the biology and disease mechanisms of coronavirus is vital for developing effective treatment protocols. Accessible syntheses of emerging viral data help researchers, clinicians, and the broader community stay informed, improving the coordination of public health responses and accelerating the identification of viable therapeutic options during major health crises.
The abstract does not indicate an application pathway or specific commercial product, as it focuses on providing a generalised literature review of viral mechanisms and potential therapeutics.
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Nowadays, the coronavirus epidemic represents a major threat to the human being, represented by great numbers of deaths and wide world life disrupt. COVID-19 virus, is not only representing a threat to the life of human being, but also to the economic activities that nearly stopped in many countries due to the partial to complete closure of life activities in order to control the wide spread of virus infections. In these extraordinary and unprecedented critical times of human being life, it is essential to review and discus the virus epidemic in trial to suggest an idea that might be beneficial to researchers to find out an exit from this dark tunnel and to prevent as possible epidemic recurrence. Many attempts of management protocols and trials all over the world, nearly failed until now to control the wide spread and the high incidence of morbidity and mortality of this viral infection. In this review, we highlight the virology and pathogenesis of epidemic and possible used therapeutics in a simplified and concise form to be easily understood and available for healthcare members and even general population. This might help in control and eradication of the current epidemic.
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DOI: 10.21608/aeji.2020.93432
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