Contrôle de qualité des produits sanguins labiles : Expérience de la banque de sang de l’hôpital régional de Zaghouan

Abstract

Introduction-Aim : Quality control of blood products (BP) is a fundamental element in guaranteeing transfusion efficacy. The aim of our study was to evaluate the quality of red blood cell concentrates (RBCs) and fresh plasma (FP) produced at the Zaghouan blood bank, with reference to the requirements of the guide to good transfusion practices and international standards. METHODS: This is a cross-sectional study carried out at the Zaghouan blood bank. The first six bags of whole blood collected were selected. The volume of RBCs and FP were measured with an electronic balance and the hematocrit rate and hemoglobin content of RBCs were determined using a Mindray BC-5800 automated system. RESULTS: According to Tunisian standards, RBC volume, haemoglobin content, and haematocrit were compliant in 94.25%, 60.75%, and 95.5% of cases, respectively. These parameters met the European standards in 91.5%, 60.75%, and 44% of cases, respectively. The volume of 300 FPs complied with 93.6% and 100% of the European and Tunisian standards, respectively. Among 400 RBC units, 60.75% and 41.25% were compliant with Tunisian and international standards, respectively. CONCLUSIONS: Quality control enabled us to identify non-conformities in the RBCs produced. We therefore recommend adjusting the volume of plasma extracted after whole blood centrifugation, including pre-donation haemoglobin levels in donor eligibility criteria, and extending the interval between two successive donations.