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article · Nigerian Dental Journal

Conservative Management of Pediatric Unicystic Ameloblastoma in a Secondary Healthcare Facility in an Ameloblastoma's High Burden Sub-Saharan Africa: A Report of Two Cases

In plain language

This research describes a conservative management approach for unicystic ameloblastoma (UA) in paediatric patients, aiming to prevent facial disfigurement and complications often associated with surgical resection. The method involves a combination of marsupialisation, enucleation, and adjuvant therapy with Carnoy's solution. Two cases from Nigeria are presented: a 13-year-old boy and an 11-year-old boy, both diagnosed with unicystic mural ameloblastoma in the mandible. Following the intervention, postoperative imaging showed restored bony trabeculae, and there was no clinical or radiographic evidence of recurrence after one year of follow-up. This approach is noted to improve patients' quality of life by restoring jawbone health.

Key takeaways

  • Conservative management of unicystic ameloblastoma (UA) can prevent facial disfigurement and complications.
  • A combination of marsupialisation, enucleation, and Carnoy's solution can restore jawbone health in UA patients.
  • Two paediatric cases in Nigeria showed successful treatment with no recurrence after one year using this conservative approach.
  • Postoperative imaging confirmed restored bony trabeculae in the treated areas.

Why it matters

This study offers a less invasive treatment option for children with a specific type of jaw tumour, unicystic ameloblastoma. By avoiding extensive surgery, it helps prevent facial disfigurement and other complications, significantly improving the quality of life for young patients and restoring their jawbone health.

Commercialisation angle

The abstract describes a clinical treatment protocol for unicystic ameloblastoma. It does not indicate an application pathway for commercialisation in terms of a new product or service, but rather an improved clinical practice.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

Background: Surgical resection is the primary treatment for ameloblastoma but often causes facial disfigurement and complications. Conservative management of unicystic ameloblastoma (UA) may prevent these issues. Clinicians should note that combining marsupialization, enucleation, and Carnoys solution adjuvant therapy restores jawbone health, prevents complications, and improves patients quality of life. Presentation: Two pediatric casesa 13-year-old boy with a 3-month right mandibular ramus swelling and an 11-year-old boy with a 5-month anterior mandibular swellingpresented at General Hospital Ifako-Ijaiye. Clinical and investigative findings confirmed unicystic mural ameloblastoma. Intervention: Both underwent marsupialization followed by enucleation with Carnoys solution. Preoperative orthopantomograms showed unilocular radiolucent lesions; postoperative imaging revealed restored bony trabeculae. Outcome: Successful treatment with no recurrence after one year (ongoing monitoring). There was no clinical or radiographic evidence of recurrence at 1-year follow-up. Planned surveillance per IAOMS guidelines (≥5 years for mural UA)" Conclusion: Conservative UA management with regular follow-up prevents facial disfigurement and complications associated with resection, improving quality of life. These are Nigeria’s first documented pediatric UA cases. Keywords: unicystic ameloblastoma, marsupialization, enucleation, Carnoys solution.

Research topics

  • Oral and Maxillofacial Pathology
  • Tumors and Oncological Cases
  • Oral and Craniofacial Lesions

Read the original research

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DOI: 10.61172/a6xqq144

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