article · Journal of Clinical Sciences
Congenital prepubic sinus is an uncommon congenital anomaly affecting the external genital organs, marked by an opening on the dorsum that typically discharges purulent fluid. While the condition can occur in both males and females, its underlying cause remains uncertain, though theories suggest a link to urethral duplication based on earlier immunohistochemical findings of transitional epithelium. This report reviews two male paediatric cases featuring pustular-looking lesions on the dorsum of the penile shaft. In both instances, clinicians cannulated, skeletonised, and entirely excised the sinus tracts. Postoperative histological analyses identified stratified squamous epithelium lining the tracts. Because of the rarity of this condition, diagnosis relies on a high index of clinical suspicion. Complete surgical removal of the tract serves as the definitive treatment to ensure the anomaly does not recur.
Due to its rarity, congenital prepubic sinus can be difficult to recognise and may be confused with other conditions. Sharing clinical experiences and histological details helps medical practitioners maintain a high index of suspicion. Understanding that total surgical excision of the tract resolves the condition provides surgeons with clear guidance to avoid disease recurrence in paediatric patients.
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ABSTRACT Congenital prepubic sinus is a rare congenital anomaly of the external genital organs, characterized by an opening on the dorsum with discharge of purulent material in most cases. The condition is not peculiar to males. The etiology behind this anomaly is still elusive, with some proposing that the anomaly is akin to urethral duplication. Immunochemistry findings revealing transitional epithelium in the mucosal lining of the sinus in some reports have corroborated this theory. We report two male pediatric cases. Each had a pustular-looking lesion on the dorsum of the penile shaft. The tracts were cannulated, skeletonized, and completely excised. The histological findings of stratified squamous epithelium were reported separately in our patients. Congenital prepubic sinus is a rare congenital penile lesion. A high index of suspicion is needed for diagnosis. The primary goal of treatment is to excise the entire tract to prevent recurrence.
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DOI: 10.4103/jcls.jcls_25_25
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