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article · Open Chemistry

Computational study of ADME-Tox prediction of selected phytochemicals from <i>Punica granatum</i> peels

202410 citationsOpen accessHassan II University Casablanca

Abstract

Abstract Pomegranate ( Punica granatum ) is one of the oldest well-known edible fruits, which has originated in Central Asia but now it has a widespread geographical distribution throughout the world. Phytochemicals are isolated from the pomegranate peels that show different nutritional and pharmaceutical properties. Absorption, distribution, metabolism, excretion, and toxicity (ADME-Tox) were performed to check the adsorption, distribution, metabolism, excretion, and toxicity of compounds. Previous studies mainly focused on the physico-chemical properties but other parameters are also important for the ADMET study. Six active phytochemicals B9 , B29 , B30 , B45 , B55 , and B70 show good ADMET properties and can be used for drug discovery in the future.

Research topics

  • Pomegranate: compositions and health benefits
  • Phytochemicals and Antioxidant Activities
  • Hibiscus Plant Research Studies

Sustainable Development Goals

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DOI: 10.1515/chem-2023-0188

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