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article · New Journal of Chemistry

Computational investigation of novel pyrimidine derivatives as potent FAK inhibitors<i>via</i>3D-QSAR, molecular docking, molecular dynamics simulation and retrosynthesis

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Abstract

Focal adhesion kinase is upregulated in various types of cancer and has become an important research target for the development of more effective anticancer drugs.

Research topics

  • Ubiquitin and proteasome pathways
  • Peptidase Inhibition and Analysis
  • Protein Degradation and Inhibitors

Sustainable Development Goals

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DOI: 10.1039/d3nj02471g

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